Scientist I, Dermatology/Immunology Job at AbbVie, Cambridge, MA

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  • AbbVie
  • Cambridge, MA

Job Description

AbbVie seeks a Scientist I to join the Dermatology Discovery team in Cambridge, MA, contributing to identification and validation of novel therapeutics for inflammatory skin diseases. The role combines transcriptomic analysis with in vitro mechanistic studies to advance preclinical research in hidradenitis suppurativa and psoriasis.

Responsibilities

  • Conduct sterile cell culture work with cell lines and primary human/murine cells
  • Process and analyze ex vivo human tissues for disease-relevant endpoints
  • Perform molecular and protein analyses using flow cytometry, qPCR, and multiplex assays
  • Develop assays to monitor cellular processes and analyze data using statistical methods
  • Maintain detailed experimental records and communicate findings through presentations

Requirements

  • Bachelor's degree in molecular biology, immunology, or biological sciences with 5 years of experience
  • Master's degree with 2 years of experience preferred
  • Hands-on expertise in cell culture techniques and sterile laboratory practices
  • Proficiency with flow cytometry, quantitative PCR, ELISA, Western blotting, and microscopy
  • Prior experience with keratinocytes, fibroblasts, immune cells, and Th17 differentiation preferred
  • Experience developing and implementing assays for cellular process monitoring

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